1. Package leaflet: Information for the user. AVONEX 30 micrograms/ ml solution for Injection. (Interferon beta-1a). Pre-filled syringe. Read all of this leaflet. Package leaflet: Information for the user. AVONEX 30 micrograms/ml solution for injection in pre-filled pen. (Interferon beta-1a). Pre-filled pen. Read all of this. Formal hepatic drug metabolism studies with AVONEX PS/AVONEX PEN in This leaflet is part III of a three-part “Product Monograph”.

Author: Bashicage Shaktirisar
Country: Paraguay
Language: English (Spanish)
Genre: Medical
Published (Last): 15 September 2011
Pages: 367
PDF File Size: 8.88 Mb
ePub File Size: 14.52 Mb
ISBN: 228-1-69204-262-8
Downloads: 36297
Price: Free* [*Free Regsitration Required]
Uploader: Dishura

Discard if the reconstituted product contains particulate matter or is discolored. It may be possible for your doctor to prescribe you a shorter and thinner needle depending on your body type. The manufacturer offers complimentary services including injection training and reimbursement support.

Avonex CMI | Mobile

Local skin reactions may be reduced inseert applying ice or a cold compress to the site after injection. Abortifacient activity, menstrual irregularities, anovulation, and decreased serum progesterone levels have been observed in some animal studies, including studies in rhesus monkeys, during high dose use. A problem with your heart. Sodium phosphate monobasic and dibasic.

In addition, interferon beta may bind to a distinct receptor packkage does not interact with interferon alpha.

Used to treat depression. Consider the benefits of breast-feeding, the risk of potential infant xvonex exposure, and the risk of an untreated or inadequately treated condition. To help further reduce these symptoms, your doctor may advise you to take a medication to reduce pain and inflammation before your injection and for up to one day afterwards.


PDR Search

A titration device will only allow the administration of a fraction of the full syringe contents. Titrate patients to the full dose over a 4-week period using the Rebif titration xvonex, which contains 6 doses of 8.

Use appropriate aseptic technique for preparation of solution. There is some evidence that interferon beta has greater in vitro antiproliferative effects against many solid tumor cell lines than interferon alpha.

We’re strengthening digital security to protect you.

They occur with long-term treatment. A long-term follow-up assessment was conducted at year 7 or 8 from the original PRISMS trial; data were available for of the patients and of the were still taking interferon beta-1a subcutaneously 3 times weekly. As an alternative, to reduce the incidence and severity of flu-like symptoms, treatment may be initiated with an IM dose of 7. If he or she recommends that you take a medication to reduce symptoms of pain and inflammation, follow their advice carefully.

Some formulations of interferon beta-1a contain human albumin and are contraindicated in patients with albumin hypersensitivity. If self-injecting, rotate between thighs. Do not use a double dose to make up for the dose that you missed.

That affects the bone marrow. Recovery may be complete or incomplete. Interferons and efavirenz can both cause hepatotoxicity. Increased sweating or flushing.

This may have a favorable effect on remyelination. Interferons and anti-retroviral nucleoside reverse transcriptase inhibitors NRTIs are also associated with hepatotoxicity. The dose may be gradually re-escalated when enzyme levels have normalized. Use of interferons during pregnancy should be avoided due to the risk of spontaneous abortion. Tell your doctor or pharmacist if you notice anything that is making you feel inserrt.


Digital Security

Use caution in using interferon beta-1a during breast-feeding, though clinical data suggest the drug may be used when needed by the mother. Moderate Concurrent use of chloroquine and interferons is not recommended as there is an increased risk of retinal toxicity. Your Name Your name is required.

Do not inject the area near the navel or waistline. Closely monitor patients for treatment-associated toxicities, especially hepatic decompensation. Padkage 1 ml of reconstituted solution into a syringe. The safety and efficacy avnex natalizumab as an add-on therapy to interferon beta treatments has not been established. Beta2-microglobulin, neopterin, and tryptophan, and inhibition of concanavalin-stimulated proliferation of peripheral blood mononuclear cells.

It does not take the place of talking to your specialist, doctor or pakcage. Tell any other doctors, dentists and pharmacists who treat you that you are using this medicine.

Bictegravir; Emtricitabine; Tenofovir Alafenamide: However, a small number of nursing mothers receiving interferon beta-1a reported no adverse effects in their partially breast-fed infants, and the amount of interferon beta-1a excreted into breast milk appeared to be insignificant. A case of fulminant hepatic failure requiring liver transplantation in a patient who initiated interferon beta-1a therapy while taking other potentially hepatotoxic medications has been reported from a non-U.

Wash hands prior to handling Dose Pack contents.